Analytical evaluation of a new Microdisk™ technology-based multiplex HPV genotyping system – the QPLEX™ HPV genotyping kit
نویسندگان
چکیده
منابع مشابه
Clinical utility of HPV genotyping.
Cervical cancer screening is presently done by finding abnormal cells in cervical smears (i.e., cervical cytology or Pap smears). However, cervical cytology is not full-proof. Cervical cytology is insensitive for the detection of cancer and precancer [1], requiring many rounds of screening to achieve programmatic effectiveness. It is now recognized that virtually all cervical cancers, both of t...
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The need for accurate genotyping of human papillomavirus (HPV) infections is becoming increasingly important, since (i) the oncogenic potential among the high-risk HPV genotypes varies in the pathogenesis of cervical cancer, (ii) monitoring multivalent HPV vaccines is essential to investigate the efficiency of the vaccines, and (iii) genotyping is crucial in epidemiologic studies evaluating HPV...
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The results of the genital human papillomavirus (HPV) detection in 439 cervical samples by cervical cytology were compared with sequencing analysis and a newly developed HPV genotyping 9G membrane test. The excellent sensitivity and specificity of the HPV genotyping 9G membrane test was assured by a signal to noise ratio of more than 300 and a target hybridization to non-target hybridization ra...
متن کاملDevelopment of a Bead-Based Multiplex Genotyping Method for Diagnostic Characterization of HPV Infection
The accurate genotyping of human papillomavirus (HPV) is clinically important because the oncogenic potential of HPV is dependent on specific genotypes. Here, we described the development of a bead-based multiplex HPV genotyping (MPG) method which is able to detect 20 types of HPV (15 high-risk HPV types 16, 18, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68 and 5 low-risk HPV types 6, 11, ...
متن کاملThe role of Human papilloma virus (HPV) genotyping in recurrent respiratory papillomatosis in Rasoul Akram Hospital
Background: The most common laryngeal mass in children is recurrent respiratory papillomatosis (RRP). Studies have attempted to correlate viral typing and its aggressiveness. Method: 29 patients with histologically confirmed RRP enrolled in adjuvant therapies. Patients underwent several surgical interventions. Results: HPV genotyping demonstrated 45% HPV-6 and 55% HPV-11. The mean age at the ...
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ژورنال
عنوان ژورنال: Journal of Laboratory Medicine
سال: 2019
ISSN: 2567-9449,2567-9430
DOI: 10.1515/labmed-2019-0038